Zoldix (5mg/100ml) IV Infusion | [For oste Price in Bangladesh | ePharma
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Home Medicines Osteoporosis Zoldix (5mg/100ml) IV Infusion | [For osteoporosis]

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Zoldix (5mg/100ml) IV Infusion | [For osteoporosis] Price in Bangladesh

Generic: Zoledronic Acid

Type: Infusion

Pack Size: 1 Pc

Zoledronic Acid is a potent bisphosphonate that inhibits osteoclast-mediated bone resorption. Its action is due to a strong affinity for mineralized bone, particularly at sites of high turnover. The primary molecular target is farnesyl pyrophosphate synthase in osteoclasts, leading to reduced bone breakdown. Its long duration of effect is attributed to strong binding with bone mineral.

Discount Price: ৳ 5,760
MRP: ৳ 6000 4% Off

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  • Cash on Delivery Cash on Delivery - All over Bangladesh
  • Regular Delivery Regular Delivery: 24-48 Hours, Dhaka City* Charge Tk.39-59
  • Regular Delivery Regular Delivery: 48-96 Hours, Other Cities* Charge Tk.99-125

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✅ Description:

Zoldix is prescribed for:

  • Treatment and prevention of postmenopausal osteoporosis
  • Increasing bone mass in men with osteoporosis
  • Management and prevention of glucocorticoid-induced osteoporosis
  • Treatment of Paget’s disease of bone in both men and women

Limitations of use: The optimal duration of therapy is not clearly established. For patients at low fracture risk, discontinuation should be considered after 3–5 years of use.

  • Pediatric: Not indicated.
  • Geriatric: Monitor renal function closely.
  • Renal impairment: Contraindicated if CrCl <35 mL/min.
  • Hepatic impairment: No adjustment needed (not metabolized hepatically).
  • Pregnancy & Lactation: Contraindicated – may cause fetal harm and not recommended during breastfeeding.

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✔️ Dosage & Administration | Zoldix

Postmenopausal Osteoporosis (treatment): 5 mg IV infusion once yearly (≥15 minutes).

Postmenopausal Osteoporosis (prevention): 5 mg IV infusion every 2 years.

Osteoporosis in Men: 5 mg IV infusion once yearly.

Glucocorticoid-Induced Osteoporosis: 5 mg IV infusion once yearly.

Paget’s Disease: A single 5 mg IV infusion (≥15 minutes).

Re-treatment may be required if symptoms return or serum alkaline phosphatase fails to normalize.

Supplementation:

Patients should receive Calcium (≥1200–1500 mg/day) and Vitamin D (800–1000 IU/day), particularly during the first 2 weeks after infusion.

Administration guidelines:

  • Infusion time must be ≥15 minutes.
  • Ensure patients are well-hydrated.
  • Flush IV line with 10 mL normal saline post-infusion.
  • Avoid mixing with calcium-containing solutions.
  • If refrigerated, bring to room temperature before use.
✔️ Side Effects | Zoldix

Common (>10%): Pyrexia, myalgia, headache, arthralgia, extremity pain
Others: Flu-like illness, nausea, vomiting, diarrhea, eye inflammation
Serious: Osteonecrosis of the jaw (ONJ), atypical femur fractures, renal impairment

✔️ Drug Interactions
  • Aminoglycosides: Prolonged hypocalcemia risk.
  • Loop diuretics: Increased risk of hypocalcemia.
  • Nephrotoxic drugs: Enhanced renal toxicity.
  • Renally cleared drugs: Increased exposure in renal impairment.
✔️ Overdose Management

Overdosage may result in renal failure, hypocalcemia, hypophosphatemia, and hypomagnesemia. Treat with IV supplementation (calcium gluconate, phosphate, magnesium sulfate). Maximum single dose: 5 mg IV over ≥15 minutes.

✔️ Storage
  • Store below 30°C, protected from light and moisture.
  • Keep out of reach of children.
  • Once opened, the solution is stable for 24 hours at 2–8°C.
Frequently Asked Questions (FAQ)

The latest Zoldix (5mg/100ml) IV Infusion | [For osteoporosis] price in Bangladesh is shown on this page. Price may change depending on stock, pack size, and active offers.

Yes, you can order Zoldix (5mg/100ml) IV Infusion | [For osteoporosis] online from ePharma when it is available in stock. Delivery options depend on your location in Bangladesh.

Prescription requirements can vary by product type. Please follow the product label and consult a qualified healthcare professional when needed.

Zoldix (5mg/100ml) IV Infusion | [For osteoporosis] is from ACI Limited. Please check the product details section for updated manufacturer and product information.

The listed pack size for Zoldix (5mg/100ml) IV Infusion | [For osteoporosis] is 1 Pc.
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⚠️Disclaimer:
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