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Esomeprazole MUPS Tablet
- Gastro-esophageal Reflux Disease (GERD)
- NSAID-associated gastric ulcer risk reduction
- H. pylori eradication (as part of triple therapy)
- Zollinger-Ellison syndrome & idiopathic hypersecretion
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Regular Delivery - 12-24 Hours, Dhaka City*- Regular Delivery - 24-48 Hours, All Over Bangladesh*
ফ্রি ডেলিভারিঃ - ৯৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে- ফ্রি ডেলিভারিঃ - ২৯৯৯ টাকা+ অর্ডারে, ঢাকার
বাহিরে
✅ Description:
Esomeprazole is a proton pump inhibitor (PPI) that blocks the gastric H⁺/K⁺-K-ATPase enzyme in parietal cells, thereby suppressing gastric acid secretion. It is highly effective in treating and preventing gastric and duodenal ulcers, including those associated with NSAID use.
- Othera 20 mg: Each MUPS tablet contains Esomeprazole 20 mg (as Esomeprazole Magnesium Trihydrate USP).
- Othera 40 mg: Each MUPS tablet contains Esomeprazole 40 mg (as Esomeprazole Magnesium Trihydrate USP).
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Side Effects:
Common: headache, abdominal pain, diarrhea, constipation, nausea, flatulence, dry mouth.
Long-term use (>1 year) may slightly increase risk of hip, wrist, or spine fractures.
✔️ Dosage & Administration
GERD / Erosive Esophagitis (Adults ≥18 yrs): 40 mg once daily for 4 weeks
Maintenance (Adults ≥18 yrs): 20 mg once daily
NSAID ulcer risk reduction (Adults): 20 mg once daily for 4–8 weeks
H. pylori eradication (Triple therapy): 20 mg twice daily for 7 days (with Amoxicillin 1000 mg & Clarithromycin 500 mg)
Zollinger-Ellison syndrome: 40–80 mg twice daily
Children (1–11 yrs): 10–20 mg once daily depending on weight & condition
Not recommended in children <1 year
Administration note:
Swallow whole with water; do not chew or crush. Can be dispersed in half a glass of non-carbonated water and taken immediately (within 30 min).
✔️ Pregnancy & Lactation
Use with caution during pregnancy.
Excretion in breast milk not confirmed – caution advised in nursing mothers.
✔️ Contraindications:
Hypersensitivity to esomeprazole or formulation components.
✔️ Drug Interactions
- May affect absorption of drugs requiring acidic pH (e.g., ketoconazole, digoxin, iron salts).
- May reduce clearance of diazepam (CYP2C19 substrate).
- Combination with clarithromycin + amoxicillin increases the plasma concentration of both esomeprazole and clarithromycin metabolite.
- No major interactions with phenytoin, warfarin, quinidine, clarithromycin, or amoxicillin.
✔️ Precautions & Warnings
Use with caution in patients with severe liver dysfunction or renal impairment.
Monitor if used long-term due to potential fracture risk.
✔️ Storage:
Store below 25°C in a cool, dry place, protected from light. Keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
📦Pricing Information, Availability:
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