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Itrazole 100 mg Capsule is an antifungal medicine containing Itraconazole, used to treat a wide range of fungal infections in the body. It works by inhibiting the enzymes essential for fungal cell membrane formation, leading to disruption of fungal growth and ultimately killing the fungus.
Itraconazole blocks the synthesis of ergosterol, a key component of fungal cell membranes. This weakens and damages the fungal cells, causing leakage of cell contents and eventual fungal cell death.
Liver disease: Use with caution; long-term therapy may require liver function monitoring.
Kidney disease: Use carefully in patients with renal impairment.
Heart conditions: Caution in patients with heart failure or related cardiac disorders.
Pregnancy & breastfeeding: Not recommended unless specifically advised by a doctor.
Children (<12 years) & elderly patients: Generally not recommended, except under medical supervision.
Avoid alcohol during therapy.
Do not drive or operate heavy machinery if experiencing dizziness, blurred vision, or hearing issues.
Common:
Serious (seek medical advice immediately):
Numbness, tingling, or weakness in limbs
Signs of liver damage: severe fatigue, abdominal pain, yellowing of skin/eyes (jaundice), dark urine, pale stools, loss of appetite
Allergy to itraconazole or any capsule component
Severe liver failure
Severe heart disease (especially congestive heart failure)
Concurrent use with certain interacting drugs (see below)
Itrazole has multiple drug interactions. Inform your doctor if you are taking:
Allergy medicines: terfenadine, astemizole, ebastine, mizolastine
Cholesterol-lowering drugs (statins): simvastatin, lovastatin, atorvastatin
Anti-arrhythmic drugs: quinidine, dofetilide, dronedarone
Migraine drugs: ergotamine, eletriptan, dihydroergotamine
Blood thinners: warfarin, dabigatran, rivaroxaban, ticagrelor
Immunosuppressants: cyclosporine, tacrolimus, sirolimus
HIV medicines: ritonavir, darunavir, saquinavir
Tuberculosis medicines: rifampicin, rifabutin, isoniazid
Anti-epileptics: phenytoin, carbamazepine, phenobarbital
Stomach acid medicines: omeprazole, pantoprazole, H2 blockers, antacids
Other interacting drugs include fentanyl, colchicine, sildenafil, quetiapine, St. John’s Wort, and many more.
✅ Key Reminder: Always follow your doctor’s instructions, complete the full course of therapy, and avoid self-medicating with other drugs while on Itrazole.
In case of accidental overdose, seek immediate medical attention or go to the nearest hospital.
Take exactly as prescribed by your physician.
Swallow the capsule whole with water—do not chew or crush.
Best taken after a meal for optimal absorption.
Dosage and duration depend on the type, severity, and site of infection.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.