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Reversair is prescribed for:
Long-term management and prevention of asthma.
Acute prevention of Exercise-Induced Bronchoconstriction (EIB).
Relief of symptoms of allergic rhinitis (both seasonal & perennial).
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বাহিরে
✅ Description:
Class: Selective Leukotriene Receptor Antagonist
Montelukast specifically blocks CysLT1 receptors, preventing the action of leukotrienes (LTC4, LTD4, LTE4).
This inhibition reduces airway edema, smooth muscle contraction, and inflammatory cell activation.
Clinical benefit: improves asthma control and relieves allergic rhinitis symptoms.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Dosage & Administration
Adults & Adolescents (≥15 years): 10 mg once daily.
Children 6–14 years: 5 mg once daily.
Children 2–5 years: 4 mg once daily (chewable tablet).
Children 6 months–5 years: 4 mg oral granules once daily (directly or mixed with cold water/soft food).
Elderly, renal impairment, mild-moderate hepatic impairment: No dose adjustment needed.
✔️ Side Effects
Common: Headache, diarrhea, fever, GI upset, nausea, URI, skin reactions.
Uncommon: Anxiety, dizziness, abnormal behavior, arthralgia, irritability, sleep disturbance.
Rare/Severe: Angioedema, hallucinations, hepatic dysfunction, pulmonary eosinophilia, suicidal ideation.
✔️ Interaction
Generally safe with commonly used asthma therapies and drugs such as theophylline, steroids, digoxin, warfarin, and oral contraceptives.
Phenobarbital & rifampin: Reduce plasma levels (~40%) due to hepatic enzyme induction → monitor clinically.
No major interactions reported with thyroid hormones, NSAIDs, benzodiazepines, decongestants, etc.
✔️ Contraindications:
Hypersensitivity to Montelukast or any component of the formulation.
✔️ Precautions & Warnings
Not for acute asthma attacks or status asthmaticus → patients must carry a rescue inhaler.
Can be continued during asthma exacerbations but should not replace corticosteroids abruptly.
Not to be used as sole therapy for exercise-induced bronchospasm.
Patients with aspirin-sensitive asthma must still avoid aspirin/NSAIDs.
Caution in pregnancy & lactation—use only if clearly needed.
✔️ Storage:
Store below 30°C, in a cool, dry place away from moisture and light.
Keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
